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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Salazar, José | SS | Louisville Bats | 26 | 02/08/2000 | Boca Chica | DOM | Right | Right | 6' 2" | 195 lbs | - |
| Salinas, Jorge | LF | Charlotte Knights | 25 | 10/28/2000 | Guaymate | DOM | Right | Right | 6' 1" | 205 lbs | $750,000 |
| Sanchez, Manny | RF | Free Agent | 30 | 10/06/1995 | San Juan de la Maguana | DOM | Right | Right | 6' 2" | 220 lbs | - |
| Sandoval, Nate | SP | Durham Bulls | 26 | 12/02/1999 | Chicago | USA | Switch | Right | 6' 2" | 200 lbs | $750,000 |
| Santos, Jesús | 2B | Columbus Clippers | 26 | 09/18/1999 | Santiago | DOM | Right | Right | 6' 2" | 200 lbs | $750,000 |
| Schaefer, Danny | 1B | Lehigh Valley IronPigs | 32 | 09/05/1993 | Fairborn | USA | Left | Left | 6' 2" | 220 lbs | - |
| Schmidt, Ezra | SP | Louisville Bats | 29 | 10/12/1996 | Statesville | USA | Left | Left | 6' 4" | 215 lbs | $750,000 |
| Scott, Don | RP | Toledo Mud Hens | 25 | 11/02/2000 | Perryton | USA | Right | Right | 6' 5" | 205 lbs | - |
| Scott, Tim | SS | Toledo Mud Hens | 23 | 04/02/2003 | West Springfield | USA | Right | Right | 5' 10" | 155 lbs | $750,000 |
| Sepulveda, Carlos | 2B | Lehigh Valley IronPigs | 29 | 08/27/1996 | Monclova | MEX | Left | Right | 5' 10" | 180 lbs | - |
| Sheehan, Dan | CF | Louisville Bats | 26 | 09/25/1999 | Parsippany-Troy Hills Township | USA | Left | Right | 6' 4" | 205 lbs | $750,000 |
| Sheffield, Justus | SP | Free Agent | 29 | 05/13/1996 | Tullahoma | USA | Left | Left | 5' 10" | 200 lbs | - |
| Shiplack, Emmitt | 2B | Norfolk Tides | 25 | 12/14/2000 | Markham | CAN | Switch | Right | 6' 3" | 205 lbs | $750,000 |
| Shirokata, Chris | 2B | Toledo Mud Hens | 24 | 12/23/2001 | Athens | USA | Left | Right | 6' 1" | 195 lbs | - |
| Silva, Álex | 1B | Pawtucket Red Sox | 26 | 07/23/1999 | Ponce | PUR | Left | Left | 6' 0" | 200 lbs | - |
| Simmons, Andrelton | SS | Lehigh Valley IronPigs | 36 | 09/04/1989 | Unknown | ANT | Right | Right | 6' 2" | 150 lbs | - |
| Simmons, Ben | SS | Scranton WB RailRiders | 28 | 11/02/1997 | Tehachapi | USA | Left | Right | 6' 4" | 205 lbs | - |
| Singleton Jr., Chris | C | Lehigh Valley IronPigs | 31 | 08/09/1994 | Barnstable Town | USA | Left | Right | 6' 3" | 210 lbs | - |
| Sisco, Chance | C | Free Agent | 31 | 02/24/1995 | Corona | USA | Left | Right | 6' 0" | 200 lbs | - |
| Skaggs, Tyler | SP | Pawtucket Red Sox | 34 | 07/13/1991 | Santa Monica | USA | Left | Left | 6' 4" | 205 lbs | - |
| Smart, Jarred | SP | Free Agent | 30 | 11/23/1995 | Fayetteville | USA | Left | Left | 6' 4" | 210 lbs | - |
| Smiley, Dave | SP | Free Agent | 28 | 03/17/1998 | Inglewood | USA | Right | Right | 6' 0" | 190 lbs | - |
| Smith, Ernie | SP | Buffalo Bisons | 24 | 04/26/2001 | Brooklyn | USA | Left | Right | 5' 11" | 185 lbs | - |
| Smith, Jeff | C | Lehigh Valley IronPigs | 29 | 12/07/1996 | Fond du Lac | USA | Right | Right | 5' 11" | 200 lbs | - |
| Smith, Jerry | CF | Toledo Mud Hens | 24 | 05/03/2001 | Leawood | USA | Left | Left | 6' 2" | 195 lbs | - |
| Smith, Tony | RP | Lehigh Valley IronPigs | 24 | 11/21/2001 | Alamosa | USA | Right | Right | 6' 2" | 205 lbs | - |
| Smith, Tony | 1B | Charlotte Knights | 24 | 10/06/2001 | Boise | USA | Left | Left | 6' 1" | 195 lbs | - |
| Sosa, Edmundo | 2B | Free Agent | 30 | 03/06/1996 | Panama | PAN | Right | Right | 5' 11" | 190 lbs | - |
| Soto, William | RP | Louisville Bats | 30 | 02/13/1996 | Punto Fijo | VEN | Right | Right | 6' 4" | 200 lbs | - |
| Stanford, Oscar | SP | Indianapolis Arrows | 25 | 01/29/2001 | Columbus | USA | Right | Right | 6' 4" | 200 lbs | $750,000 |
| Stanley, Steve | 2B | Free Agent | 32 | 09/22/1993 | Binghamton | USA | Switch | Right | 6' 1" | 190 lbs | - |
| Starks, Mike | CF | Scranton WB RailRiders | 28 | 11/23/1997 | Donalsonville | USA | Right | Right | 6' 3" | 200 lbs | - |
| Stevens, Thom | SP | Syracuse Chiefs | 25 | 08/30/2000 | Philadelphia | USA | Right | Right | 6' 0" | 185 lbs | $750,000 |
| Stevenson, Dan | SS | Durham Bulls | 25 | 11/25/2000 | Lebanon | USA | Right | Right | 6' 1" | 195 lbs | - |
| Stewart, Ron | SP | Charlotte Knights | 25 | 01/28/2001 | Ewa Beach | USA | Switch | Right | 6' 7" | 210 lbs | - |
| Strickland, Norm | RP | Norfolk Tides | 29 | 12/07/1996 | Highland Mills | USA | Switch | Right | 5' 10" | 195 lbs | $750,000 |
| Stuart, Champ | LF | Free Agent | 33 | 10/11/1992 | Nassau | BAH | Right | Right | 6' 0" | 200 lbs | - |
| Stuckey, Harry | RP | Rochester Red Wings | 24 | 12/14/2001 | Napa | USA | Right | Right | 6' 6" | 205 lbs | - |
| Suarez, Sergio | RP | Scranton WB RailRiders | 30 | 05/24/1995 | Ciudad Ojeda | VEN | Left | Left | 6' 0" | 195 lbs | - |
| Szkutnik, Trent | RP | Indianapolis Arrows | 32 | 08/21/1993 | Jackson | USA | Right | Left | 6' 0" | 200 lbs | - |
| Sánchez, Pete | 1B | Charlotte Knights | 24 | 09/18/2001 | Lancaster | USA | Left | Right | 5' 10" | 170 lbs | - |
