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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sackett, Shaun | RP | Free Agent | 25 | 07/13/2000 | Jennings | USA | Right | Right | 5' 9" | 175 lbs | - |
| Salazar, Robinson | RP | Staten Island Yankees | 21 | 02/18/2004 | Villa Altagracia | DOM | Right | Right | 6' 6" | 195 lbs | - |
| Sandberg, Jim | SP | State College Spikes | 22 | 06/08/2003 | Jacksonville | USA | Left | Left | 6' 5" | 205 lbs | - |
| Sandoval, Dave | LF | West Virginia Black Bears | 25 | 02/16/2000 | Cambridge | USA | Right | Right | 6' 0" | 200 lbs | - |
| Santos, Ismael | SP | Lowell Spinners | 21 | 11/20/2003 | Santo Domingo | DOM | Left | Left | 6' 2" | 185 lbs | - |
| Santos, Manny | RP | Vermont Lake Monsters | 20 | 02/12/2005 | Santo Domingo | DOM | Switch | Right | 6' 2" | 180 lbs | - |
| Scofield, Eddie | RP | Free Agent | 21 | 11/16/2003 | Jefferson | USA | Right | Right | 5' 10" | 160 lbs | - |
| Scott, Alvin | 1B | Hudson Valley Renegades | 23 | 05/03/2002 | St. Augustine Beach | USA | Right | Right | 6' 2" | 200 lbs | - |
| Scott, Ed | RP | Lowell Spinners | 25 | 12/19/1999 | Hollister | USA | Left | Left | 6' 0" | 185 lbs | - |
| Selem, Mauro | C | Brooklyn Cyclones | 21 | 07/11/2004 | Chichigalpa | NCA | Right | Right | 5' 10" | 185 lbs | - |
| Sharpe, Ron | 3B | State College Spikes | 21 | 10/19/2003 | New York | USA | Right | Right | 6' 0" | 200 lbs | - |
| Shoemake, Don | RP | Auburn Doubledays | 20 | 10/24/2004 | Houston | USA | Left | Left | 6' 2" | 180 lbs | - |
| Silva, Nelson | 2B | West Virginia Black Bears | 23 | 05/27/2002 | Cataño | PUR | Right | Right | 6' 3" | 205 lbs | - |
| Silver, Cliff | RP | State College Spikes | 24 | 04/20/2001 | Rochester | USA | Right | Right | 6' 0" | 185 lbs | - |
| Simmons, Jody | SP | Connecticut Tigers | 20 | 02/19/2005 | Colorado Springs | USA | Right | Right | 6' 0" | 175 lbs | - |
| Simpson, Johnathan | SS | Lowell Spinners | 23 | 07/27/2002 | Jacksonville | USA | Right | Right | 6' 2" | 190 lbs | - |
| Sims, Andy | CF | Auburn Doubledays | 19 | 07/08/2006 | Crest Hill | USA | Right | Right | 6' 6" | 190 lbs | - |
| Sims, Jeff | LF | Staten Island Yankees | 23 | 02/08/2002 | Solvay | USA | Right | Right | 6' 1" | 190 lbs | - |
| Skinner, Scotty | 1B | Mahoning Valley Scrappers | 23 | 09/30/2001 | Goodings Grove | USA | Right | Right | 6' 4" | 220 lbs | - |
| Smith, Dan | 2B | Staten Island Yankees | 24 | 05/16/2001 | Charleston | USA | Left | Right | 6' 1" | 190 lbs | - |
| Smith, Jerry | RP | Auburn Doubledays | 24 | 07/04/2001 | Greenville | USA | Right | Right | 5' 10" | 180 lbs | - |
| Smith, Marc | 1B | Mahoning Valley Scrappers | 24 | 06/26/2001 | Portland | USA | Left | Left | 6' 2" | 205 lbs | - |
| Snyder, Billy | 2B | Free Agent | 25 | 03/11/2000 | Whitehall | USA | Right | Right | 6' 0" | 195 lbs | - |
| Sosa, Pancho | RP | Connecticut Tigers | 22 | 06/12/2003 | Santo Domingo | DOM | Right | Right | 6' 4" | 200 lbs | - |
| St. John, Terrence | SP | Staten Island Yankees | 30 | 03/16/1995 | Texarkana | USA | Right | Right | 6' 1" | 200 lbs | $740,000 |
| Stephens, Jeff | RP | Hudson Valley Renegades | 23 | 08/23/2002 | New York | USA | Left | Left | 6' 4" | 200 lbs | - |
| Stevens, Jim | C | Aberdeen Ironbirds | 21 | 10/30/2003 | Longboat Key | USA | Right | Right | 6' 0" | 200 lbs | - |
| Stevens, Scotty | RP | Mahoning Valley Scrappers | 21 | 01/21/2004 | Concord | USA | Switch | Right | 6' 6" | 200 lbs | - |
| Stewart, Dave | SP | Free Agent | 25 | 01/30/2000 | Lake Charles | USA | Right | Right | 6' 5" | 210 lbs | - |
| Stroud, Billy | CF | Batavia Muckdogs | 22 | 06/10/2003 | Yucaipa | USA | Right | Right | 6' 2" | 185 lbs | - |
| Stuut, Kick | 3B | Aberdeen Ironbirds | 21 | 02/19/2004 | Oranjestad | ANT | Switch | Right | 6' 1" | 185 lbs | - |
| Sánchez, Jesús | 3B | Brooklyn Cyclones | 21 | 08/10/2004 | Santiago | DOM | Right | Right | 6' 4" | 205 lbs | - |
