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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sanford, Mike | RP | Modesto Nuts | 25 | 04/14/2000 | Carrollton | USA | Right | Right | 6' 0" | 200 lbs | - |
| Schneider, Jake | RF | Bakersfield Blaze | 24 | 05/20/2001 | Throop | USA | Left | Left | 6' 0" | 185 lbs | - |
| Seals, Sean | RF | San Jose Giants | 23 | 05/17/2002 | Austin | USA | Left | Left | 6' 4" | 200 lbs | - |
| Segura, Julián | SP | Rancho Cucamonga Quakes | 21 | 10/21/2003 | Santo Domingo | DOM | Right | Right | 6' 1" | 180 lbs | - |
| Settignano, Beniamino | SP | Modesto Nuts | 22 | 05/14/2003 | Barcelona | VEN | Right | Right | 6' 2" | 180 lbs | - |
| Sheeran, Sam | SP | Lancaster JetHawks | 25 | 03/23/2000 | Columbus | USA | Right | Right | 6' 3" | 200 lbs | - |
| Sheng, Luo-shan | C | Stockton Ports | 25 | 03/11/2000 | Meinung | TPE | Left | Right | 6' 0" | 205 lbs | - |
| Silva, Jorge | SP | Rancho Cucamonga Quakes | 22 | 04/12/2003 | Caracas | VEN | Right | Right | 6' 5" | 195 lbs | - |
| Silva, Ron | CL | Inland Empire 66ers | 25 | 03/04/2000 | Chandler | USA | Right | Right | 6' 8" | 235 lbs | - |
| Skouloudis, Timon | RP | Lancaster JetHawks | 24 | 06/10/2001 | Concord | USA | Right | Right | 6' 0" | 180 lbs | - |
| Smith, Caleb | SP | Inland Empire 66ers | 20 | 02/19/2005 | Rochester | USA | Left | Left | 6' 0" | 180 lbs | - |
| Smith, Colt | SP | Free Agent | 27 | 07/24/1998 | Lochearn | USA | Right | Right | 6' 4" | 200 lbs | - |
| Smith, Ken | CL | Rancho Cucamonga Quakes | 23 | 08/30/2002 | New York | USA | Switch | Right | 6' 4" | 210 lbs | - |
| Smith, Ted | CF | Lancaster JetHawks | 24 | 09/22/2000 | Hot Springs | USA | Left | Right | 6' 2" | 200 lbs | - |
| Smith, Tim | C | Rancho Cucamonga Quakes | 25 | 02/27/2000 | Bloomfield Township | USA | Right | Right | 6' 4" | 240 lbs | - |
| Sotos, José | 1B | Free Agent | 27 | 10/18/1997 | Olean | USA | Left | Left | 6' 4" | 225 lbs | - |
| Spencer, Dana | CF | Bakersfield Blaze | 23 | 05/31/2002 | Temple | USA | Left | Left | 6' 0" | 185 lbs | - |
| Steward, Tommy | SP | Inland Empire 66ers | 23 | 04/08/2002 | San Jose | USA | Left | Right | 6' 0" | 185 lbs | - |
| Sullivan, Dan | RP | Bakersfield Blaze | 26 | 03/10/1999 | Sanford | USA | Right | Right | 6' 3" | 200 lbs | - |
| Suárez, Jon | CL | Inland Empire 66ers | 21 | 05/22/2004 | Jackson | USA | Right | Right | 6' 5" | 200 lbs | - |
| Sáenz, Raúl | C | Lancaster JetHawks | 24 | 05/06/2001 | Caguas | PUR | Left | Right | 5' 10" | 190 lbs | - |
| Sánchez, Ernesto | RP | Modesto Nuts | 23 | 01/20/2002 | Puebla | MEX | Left | Left | 5' 10" | 175 lbs | - |
| Sánchez, Juan | RP | Stockton Ports | 22 | 12/17/2002 | Sabana Buey | DOM | Left | Left | 6' 7" | 200 lbs | - |
| Sánchez, Luis | 3B | Visalia Rawhide | 23 | 04/06/2002 | Killeen | USA | Right | Right | 6' 4" | 200 lbs | - |
| Sánchez, Sergio | RF | Rancho Cucamonga Quakes | 21 | 11/06/2003 | Russellville | USA | Left | Left | 6' 1" | 195 lbs | - |
