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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Zagomba, Antão | SS | Miami Marlins | 17 | 10/25/2007 | Valencia | VEN | Right | Right | 6' 2" | 175 lbs | - |
| Zambrano, Jesús | SP | Free Agent | 20 | 07/11/2005 | Bedford | USA | Left | Right | 5' 11" | 160 lbs | - |
| Zambrano, Juan | 3B | Free Agent | 21 | 05/12/2004 | Raleigh | USA | Right | Right | 6' 4" | 205 lbs | - |
| Zamora, Bernardo | SP | Houston Astros | 17 | 01/14/2008 | Higüey | DOM | Switch | Right | 6' 6" | 195 lbs | - |
| Zamora, Orlando | SS | Free Agent | 17 | 01/10/2008 | Alhambra | USA | Right | Right | 6' 2" | 170 lbs | - |
| Zanco, Víctor | SP | Milwaukee Brewers | 17 | 03/17/2008 | Santiago | DOM | Right | Right | 6' 2" | 175 lbs | - |
| Zapata, Jesús | CF | Miami Marlins | 18 | 11/20/2006 | Villa Bisonó | DOM | Switch | Left | 6' 3" | 200 lbs | - |
| Zapata, Jorge | 3B | Toronto Blue Jays | 16 | 03/19/2009 | Cabrera | DOM | Right | Right | 6' 2" | 180 lbs | - |
| Zaragoza, Jorge | 3B | San Diego Padres | 25 | 05/29/2000 | Río Verde Arriba | DOM | Right | Right | 6' 2" | 190 lbs | $740,000 |
| Zavala, Juan | 2B | Kansas City Royals | 18 | 06/24/2007 | San Cristóbal | DOM | Right | Right | 6' 4" | 205 lbs | - |
| Zavala, Norberto | DH | Miami Marlins | 25 | 01/11/2000 | Calabozo | VEN | Left | Right | 6' 1" | 185 lbs | $740,000 |
| Zeile, Shane | C | Free Agent | 32 | 06/14/1993 | Los Angeles | USA | Right | Right | 6' 1" | 200 lbs | - |
| Zerman, Angelo | C | San Francisco Giants | 16 | 11/01/2008 | El Tocuyo | VEN | Right | Right | 5' 10" | 185 lbs | - |
| Zhu, Li-zhu | 3B | Free Agent | 19 | 11/29/2005 | Tainan | TPE | Switch | Right | 6' 4" | 200 lbs | - |
| Zhuo, Kuang-yin | RP | Free Agent | 22 | 11/25/2002 | Ajax | CAN | Right | Right | 6' 2" | 200 lbs | - |
| Zimmer, Bradley | RF | San Francisco Giants | 32 | 11/27/1992 | San Diego | USA | Left | Right | 6' 5" | 200 lbs | $13,000,000 |
| Zimmerman, Dewitt | SP | Free Agent | 22 | 03/08/2003 | Washington | USA | Right | Right | 6' 4" | 200 lbs | - |
| Zimolo, Jorge | CF | Chicago Cubs | 17 | 03/11/2008 | Maracaibo | VEN | Switch | Right | 6' 1" | 170 lbs | - |
| Zumaya, Juan | SP | Texas Rangers | 16 | 11/21/2008 | Valencia | VEN | Right | Right | 6' 2" | 180 lbs | - |
| Zunino, Mike | C | Free Agent | 34 | 03/25/1991 | Coral Gables | USA | Right | Right | 6' 2" | 230 lbs | - |
| Zúñiga, Devlyn | 3B | Free Agent | 19 | 05/11/2006 | Glendale | USA | Right | Right | 6' 1" | 185 lbs | - |
